Hungarian Chargé d’Affaires János Radványi reports on Anastas Mikoyan’s visit to Washington, DC. After a brief description of Mikoyan’s Washington itinerary, the report is divided into three sections: Mikoyan’s impressions of his meetings with American officials, meetings in Cuba with Cuban officials, and meetings about different socialist countries (e.g. China, Hungary). Primary subjects discussed include the presence of missiles in Cuba, nuclear proliferation and Latin America as a nuclear free region, missile bases, and the Berlin issue.

Hungarian Ambassador to Cuba János Beck reports on a cocktail party at the Soviet embassy and his discussions with Anastas Mikoyan and other socialist ambassadors. The socialist ambassadors did not meet with Soviet leaders during the Cuban Missile Crisis and were not informed of developments. Beck adds that discussions at the reception did not elaborate beyond published news reports. In one instance, Beck notes that Mikoyan ignored questions about the Cuban public’s criticism of the Soviet handling of the crisis.

Khrushchev and Mikoyan discuss the Cuban Missile Crisis in this excerpt from a conversation with a Romanian delegation in Pitzunda, Georgia (now Abkhazia). They discuss the Sino-Soviet Split, and Khrushchev complains that "the Chinese qualified us as adventurers, while on other issues they call us cowards," and explains his reasoning for defending Cuba.

Drozniak reports on a conversation he had with Mikoyan about some diplomatic actions during the Cuban Missile Crisis between the Soviet Union, the United States and Cuba.

Exceprts from a Polish-Soviet talk in Moscow in April 1964 that are about the Cuban issue. Specifically, they are about each country's sugar trade values with Cuba.

The report of a conversation in Moscow between Cuban Communist Official Carlos Rafael Rodriguez and Soviet Leader Nikita Khrushchev, discussing Soviet-Cuban relations and public announcements of support.

A report from the Cuban Mission to the UN concerning a conversation with Anastas Mikoyan and US President John F. Kennedy and Secretary of State Dean Rusk. The three are mostly focused on discussing US-Latin American diplomatic relations, and concerns over American military presence in Latin America, specifically the US fly-overs. Kennedy continues to reiterate the US's position on 'no US invasion of Cuba.'

The conversation takes place soon after the IL-28 crisis, which gives Mikoyan a chance to patch up the relationship with trade agreements and promises of future aid and industrial cooperation. Near the end of the conversation, Guevara and Mikoyan discuss the theory of revolutionary struggle. Guevara shares his vision that “further development of the revolutions in Latin America must follow the line of simultaneous explosions in all countries.” Mikoyan cautions him, pointing to the Soviet experience and using the metaphor of the rebellion on the battleship “Potemkin.” Hinting at further disagreement ahead, he gently registers his disagreement with the Cuban leader’s drive to ignite revolution in the hemisphere.

The conversation was recorded after the Cuban leader refused to see the Soviet envoy for three days in a reaction to the new demand. Castro starts by declaring his disagreement with the decision to remove the IL-28s but, assures Mikoyan that the revolutionary leadership discussed the issue and agreed to the removal. Mikoyan presents all his arguments to show that the withdrawal of the planes would end the crisis and make the US non-invasion pledge more credible. He acknowledges the “negative psychological effect” of the decision and reiterates that all the rest of the weapons would stay in Cuba so its security would be guaranteed without the obsolete planes. They also agree on the rules of verification of the withdrawal.

Protocol 41 details a meeting on a group of economic advisers sent to Cuba from the Soviet Union.